Comparative Study on the Effect of 42 ℃ Intraperitoneal Hyperthermia Chemotherapy on Cancerous Ascites with Different Treatment Time
Keywords:
intraperitoneal hyperthermia chemotherapy, cancerous ascites, hyperthermia treatment timeAbstract
Objective: The difference of curative effects of 42 ℃ intraperitoneal hyperthermia chemotherapy in the treatment of cancerous ascites with different treatment time was studied to find out the best matching treatment time of hyperthermia chemotherapy.
Methods: 200 cases of patients with malignant ascites from our hospital that treated with the heat intraperitoneal chemotherapy during 2004 to 2020 were selected, among which 100 cases had hyperthermia time of 60 minutes and 100 cases had hyperthermia time of 120 minutes. The curative effects, half-year and one-year survival period, and post-treatment complications of the two groups of patients were compared and analyzed.
Results: The treatment efficiency, half-year survival and one-year survival period of the patients in the 120 minutes treatment group were significantly better than those in the 60 minutes treatment group. The data comparison and analysis showed statistical differences. However, there was no statistical difference in the adverse reactions between the two groups of patients after treatment.
References
Zhang Feifei , Kim Sai-chu , Liu handsome self . Malignant ascites New Treatment [J]. Journal of Gastroenterology and Hepatology , 2017,26 (04): 476-478.
Xiao Shaowen , Wu Zhibing , Zhang Ke . Chinese expert consensus on tumor hyperthermia [J]. Journal of Practical Oncology , 2020,35(01):1-10.
Wu Shizhen . Observation of the clinical effect of apatinib in the treatment of advanced gastric cancer with refractory cancerous ascites [J]. Journal of Clinical Rational Use , 2018,11(20):53-54.
Chen Yi , Zhu Peng , Zhang Jianbo . Research progress of intraperitoneal hyperthermic perfusion chemotherapy in the treatment of advanced gastric cancer with malignant ascites [J]. Modern Medicine and Health , 2018,34(21):3339-3341+3416.
Zhang Zetian, Xu Guangwei . Oncology [M]. Tianjin Science and Technology Press, 1999:842-850.
Weiming Qin , Xu XiMing . Hyperthermia, sorafenib joint involvement of primary liver cancer . [J] Modern Medicine , 2014,23 (36): 4006-4009.
Fan Yufei , Qin Yuan , Li Dinggang . The effect of recombinant human P53 adenovirus injection combined with local hyperthermia and chemotherapy in the treatment of advanced pancreatic cancer [J] .China Contemporary Medicine ,2017,24(13):85.
Yang Jian , Guo Xinhong , Lu Wei et al . Evaluation and analysis of clinical efficacy of interventional chemoembolization combined with extracorporeal hyperthermia for advanced liver cancer [J]. Chinese Journal of Modern Surgery , 2015,19(03):186.
Liang Anlin , Li Zhuori , Zhou Kailun , Zheng Jinfang , Sun Qigang , Wu Jincai . Hyperthermia methods and new developments in liver cancer [J]. Hainan Medicine , 2013,24(12):1789-1792.
Li Yazhe , Zhang Yang , Sun Jinghua . Research progress on the effects of deep hyperthermia on the immune function of pancreatic cancer [J] .Journal of Dalian Medical University ,2019,41(02):175.
Shen Wenming . In vitro experimental study on heating-induced apoptosis of gastric cancer cells [J]. Modern Medicine and Health ,2011,27(19):2898-2900 .
Downloads
Published
Versions
- 2021-09-23 (2)
- 2021-09-22 (1)
Issue
Section
License
Copyright (c) 2021 Journal of Research in Clinical Oncology
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
