Comparative Study on the Effect of 42 ℃ Intraperitoneal Hyperthermia Chemotherapy on Cancerous Ascites with Different Treatment Time


  • Zongzhi Liang Henan Provincial Hospital
  • Yapeng Huang
  • Junfang Pang
  • Bin Li
  • Shengnan Zhang
  • Huizhen Zhang


intraperitoneal hyperthermia chemotherapy, cancerous ascites, hyperthermia treatment time


Objective: The difference of curative effects of 42 ℃ intraperitoneal hyperthermia chemotherapy in the treatment of cancerous ascites with different treatment time was studied to find out the best matching treatment time of hyperthermia chemotherapy. 

Methods: 200 cases of patients with malignant ascites from our hospital that treated with the heat intraperitoneal chemotherapy during 2004 to 2020 were selected, among which 100 cases had hyperthermia time of 60 minutes and 100 cases had hyperthermia time of 120 minutes. The curative effects, half-year and one-year survival period, and post-treatment complications of the two groups of patients were compared and analyzed. 

Results: The treatment efficiency, half-year survival and one-year survival period of the patients in the 120 minutes treatment group were significantly better than those in the 60 minutes treatment group. The data comparison and analysis showed statistical differences. However, there was no statistical difference in the adverse reactions between the two groups of patients after treatment.


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2021-09-22 — Updated on 2021-09-23